Effortless. Precise. Discreet 


Priya was developed to help your patients pinpoint their fertile window, effortlessly and precisely.  By wirelessly capturing continuous core temperature, Priya provides a level of precision that no other ovulation prediction method can obtain. Priya allows for your patient to have a complete picture of her personal cycle and has the algorithm to detect the subtle changes that occur PRIOR to ovulation. When most fertile, the app alerts the user when she is most fertile.  


What is Priya:

“Why estimate when you can know?"

Priya is an intravaginal ring that is identical to those currently on the market. We have simply removed the hormones, and inserted a continuous temperature sensor. Your patient inserts the Priya Ring in the comfort of her home and wears it for the non-period time of her cycle. The data is automatically transferred to the iOS Priya App and sends an alert to her phone when she is most fertile.

There are no monitors, attachable extra sensors, urine strips, or replacement parts. All that is required is to pair the Priya Ring with the Priya App and insert the ring allowing for your patients to go about life as normal. Each elegant Priya Rig is worn for one month at a time. The Priya App will remind the user when it's time to remove the ring and replace with a new one if needed. The Priya Ring is for vaginal use only. 

Priya is NOT BBT. Internal, continuous, core temperature monitoring is a more precise, reliable and accurate method to identify ovulation than once-daily oral thermometers or skin measurements (1,2,3). Priya detects the crucial DIP in body temperature that occurs PRIOR to  ovulation. Priya temperature sensor and software algorithm provide a 1–2 day advantage over most ovulation predictor kits and fertility monitors. By continuously monitoring a woman’s core body temperature, the technology is able to pinpoint the window of time when she is most fertile with precision.


Priya - For the next generation

of patients seeking precise personal monitoring


PRIYA detects this decline in temperature, providing a precise yet effortless prediction of the fertile window.

  • Priya is an intravaginal ring with the same dimensions and flexibility as Estring®. The hormones were removed, and a temperature sensor was inserted. This is an OTC product.
  • Priya ring is self-inserted and worn for 1 month at a time; inserted on the last day of her period and removed on the first day of her next period.
  • Temperature is monitored every 6 minutes; the data are transferred to the Priya app on her iPhone every 2 hours; an algorithm detects the DIP in temperature 2 days prior to ovulation, and sends her a notification on her phone (and her partner’s phone if she so chooses).



  • FDA Regulated
  • Truly PREDICTS the key fertile window
  • Continuously measures core body temperature
  • Hands-off data collection eliminates human error
  • Works for women with irregular cycles
  • Easy for patients to share data results  
  • Easy for patients to use and understand


The key features will save valuable time.  Over 40% of women experience more than 7 day cycle variability. With Priya, these women are more likely to learn if they ovulate sooner- unlike LH tests where they may miss their LH surge (4). 

Current Methods


Current ovulation prediction methods are inaccurate, inconvenient, and riddled with sources of interference (5) . BBT only detects an increase in temperature that occurs after ovulation. These methods are ineffective for the significant percentage of women who have irregular cycles. According to Consumer Reports (7) , which tested eleven ovulation kits: “though most kits are labeled as having 99 percent clinical accuracy, in actual use even the best performing models are likely to detect LH surges in a considerably lower percentage of women.”


The Science Behind Priya


A pre-ovulatory decline in core temperature takes place 24-48 hours prior to ovulation (2,3). If measured accurately, this decline provides an important tool for predicting ovulation (see graph below) as intercourse during these days increases the probability of conception (6).

Women’s bodies tightly control body temperature and exhibit a striking diurnal temperature pattern. This pattern of temperature is the best studied and most reliable marker for circadian rhythm (8). Continuous core temperature monitoring can be used to predict impending ovulation by identifying a dip in body temperature (circamensal nadir) as detected with multiple continuous temperature readings 48 hours in advance of ovulation. Algorithms using core temperature have achieved a 99% sensitivity for detection of ovulation, with a 99% percent accuracy.

Mary Coyne et al conducted a study, "Circadian rhythm changes in core temperature over the menstrual cycle: method for noninvasive monitoring",  that measured core temperatures every minute over the course of an entire menstrual cycle. As you can see in their published research, a beautiful circadian rhythm could more-reliably identify the temperature changes that precede ovulation. Even more impressive was that circadian rhythm could better-detect the important DIP in temperature preceding the surge of luteinizing hormone by one or two days (2).

Oscillating temperature patterns can be measured accurately and precisely using a vaginal rings similar to what women have worn for several years.  

Priya is a mobile phone platform that uses circadian rhythm to predict ovulation. You can imagine how this technology can improve women’s health now that cell phones have the capability of receiving this powerful information.


Learn more about our story, mission and vision to transform healthcare using continuous core temperature.





  1. Validation of the ingestible VitalSense temperature capsule. Phillips – Respironics, 2009.
  2. Coyne et al. (2000). Circadian Rhythm Changes in Core Temperature over the Menstrual Cycle: Method for Noninvasive Monitoring Physiol Regulatory Integrative Com Physiol. AM J 279:1316-132.
  3. Cagnacci et al. (1997). Regulation of the 24-hour Rhythm of Body Temperature Cycles with Spontaneous and in Menstrual Gonadotropin-induced Ovulation.Fertility and Sterility 68:421-425.
  4. Johnson SR, Shaw R. (2009). Success of detection of LH surge by home ovulation tests. Fertil Steril : 92(3):S101. 
  5. American Pharmacists Assoc. (2007). Selection and Use of Home Diagnostic Products.
  6. Wilcox et al. (1995). American Pharmacists Assoc NEJM 333(23):1517-1521 5.
  7. Consumer Report (2009).
  8. Brown et al. (2000). A statistical model of the human core-temperature circadian rhythm. Am J Physiol Endocrinol Metab 279: E669–E683.


    Who is Behind Priya?


    Lauren Costantini, PhD, CEO. Lauren has held executive positions in life science companies focusing on driving products from discovery through launch. She has lead products from research though clinical, regulatory, marketing and commercialization stages, with 20+ years developing therapeutics for several indications. She plays a key role connecting early-stage companies with potential partners, venture capital and investors, as well as directing due diligence for in- and out-licensing activities. Roles include Vice President at Colorado Institute for Drug, Device and Diagnostic Development (CID4) and former faculty at Harvard Medical School.

    Don Kirkpatrick, Chairman of the Board, Prima-Temp Inc. Don is the founder and Chairman of Cadre Technologies, the largest software provider to the third-party logistics in warehouse management and distribution technology. Don is an engineering graduate of Princeton University and Director of Denver School of Science and Technology.

    Rich Pollack, CTO and Co-Founder. Rich’s engineering team developed the temperature/pressure sensor in tires for Goodyear that later evolved into Phase IV Engineering in Boulder, CO. His engineering career spans 25 years experience including wireless temperature sensors for a variety of applications and is named in over 15 patents. He founded Phase IV and three other companies.

    Wade W. Webster, MD, CMO and Co-Founder. Dr. Webster is a practicing Emergency Physician at Evergreen Hospital Medical Center, Kirkland, Washington for 21 years. He received his Medical Degree from Albany Medical College in Albany, New York. Wade is currently the Chief Science Officer for DVM Systems, LLC, a system for early disease detection and reproduction that uses temperature monitoring in dairy cattle and ruminants.